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ClearNote Health

Senior Manager/Director, Billing and Revenue Cycle Management

san diego, ca / Posted
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Job Title: Senior Manager/Director, Billing and Revenue Cycle Management

Reports to: Vice President, Market Access

FLSA: Exempt

Location: San Diego, CA (Remote)

Position Summary: ClearNote Health is an early cancer detection company focused on the development and commercialization of non-invasive epigenomic tests to detect cancer through a standard blood draw, earlier than existing methods and when the disease is still treatable. Leveraging its novel liquid biopsy technology, ClearNote Health is initially focused on high-mortality cancers with the greatest need for early detection, starting with pancreatic and ovarian cancers.

As the Senior Manager of Billing and Revenue Cycle Management, you will play a key leadership role in ensuring that ClearNote Health’s billing and reimbursement operations are compliant, efficient, and patient-centered. You will be responsible for overseeing day-to-day revenue cycle activities, managing external billing vendors, implementing performance KPIs, and partnering cross-functionally to ensure optimal reimbursement outcomes.

Responsibilities:

  • Oversee end-to-end billing operations including payer credentialing, claims lifecycle (submission, follow-up, payment posting, denials, and appeals), and appropriate patient/provider communications
  • Ensure timely, accurate, and compliant claim processing in alignment with CMS, commercial payer, and state and federal regulatory standards
  • Lead and oversee billing vendor performance, ensuring adherence to payer requirements, quality controls, timely submissions, and effective issue resolution
  • Analyze revenue cycle data and trends to drive insights and optimize reimbursement performance; communicate key findings to senior leaders including VP Market Access, CEO, CFO, and Controller
  • Collaborate cross-functionally with Market Access, Finance, Customer Service, Laboratory, and Compliance teams to ensure a proactive, seamless billing process
  • Lead billing-related customer service efforts, including triaging incoming calls and coordinating clinical questions with the Laboratory or Medical Affairs teams
  • Support and oversee ClearNote’s Patient Financial Assistance Program with empathetic and transparent communication
  • Participate in payer audits, medical record reviews, and policy updates impacting reimbursement
  • Track and report key performance indicators (KPIs) including Average Allowable Payment Rate, Average Sales Price, Days Services Outstanding (DSO), clean claim rate, denial rates, and collection trends
  • Lead or support implementation of new systems, tools, or process improvements within the revenue cycle workflow

Requirements:

  • Bachelor’s degree required, preferably in Finance, Healthcare Administration, Business, or related field
  • Minimum 7 years of experience in healthcare billing or revenue cycle management, with at least 2 years in a managerial role
  • Experience in diagnostics or laboratory billing strongly preferred (molecular or genetic testing a plus)
  • Strong understanding of CMS guidelines, commercial payer billing practices, EDI processes, and medical coding (CPT, ICD-10, HCPCS)
  • Proven experience working with and managing external billing vendors or service contracts
  • Proficiency in data analytics and reporting tools; familiarity with EMR, LIS, and billing systems
  • Exceptional organizational, communication, and leadership skills, including the ability to explain billing processes to non-technical audiences and drive process improvements cross-functionally

Our commitment to Diversity, Equity, and Inclusion:

We celebrate diversity in perspectives and backgrounds, and this is reflected in our innovation and versatility. Our differences make us unique, help us innovate, and allow us to persevere. We stand firmly behind our values, strive to achieve representation, and celebrate diversity in perspectives and backgrounds.

The anticipated salary range for this position is $145,000 to $200,000. The actual salary will be dependent on various factors that may include experience level, knowledge, skills and abilities.

ClearNote Health offers a competitive salary and benefits package.

Come join us in addressing large healthcare needs through precision epigenomic medicine!

ClearNote Health is an exciting life science company that is reinventing non-invasive molecular diagnostic testing using next generation epigenomic technologies. We are passionate and dedicated to discovering and developing medicines that will make a significant difference in cancer and other epigenomic-driven diseases. Our technologies provide novel insight and quantitation of human health and disease, with our focus on precision medicine applications improving both clinical and health system outcomes. Our company was founded based on pioneering work in the Stanford laboratory of Stephen Quake, with advisors from Stanford and UCSF.

We look for extraordinary lifelong learners with a passion and growth mindset for these areas, and for combining biological ingenuity with AI and data analysis. Led by a team with decades of experience bringing products from concept to market, we are an equal opportunity employer and value diversity at our company.

We provide generous benefits to all employees including stock options. We are building a world-class company, based in San Diego and San Mateo.

Our commitment to Diversity, Equity, Inclusion, and Belonging:

We celebrate diversity in perspectives and backgrounds, and this is reflected in our innovation, our mission, and values. Our differences make us unique, help us innovate, and allow us to persevere. We strive to achieve representation and inclusion and redefine the possible in patients living longer lives.

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